Supplementary Figure 2: TH-RREE vector increases TH expression in A53T mice.
From: Dopamine induces soluble α-synuclein oligomers and nigrostriatal degeneration
(a) TH levels were increased in the striatum in A53T TH-RREE mice compared with A53T CtrlVect at 5 mpi. GAPDH was used as a loading control. (n = 3 mice per group, P = 0.0048, t = 5.657, d.f. = 4; two-tailed unpaired Student’s t test). (b) TH staining was increased in both the SN (left panels) and striatum (right panels) of A53T TH-RREE mice at 5 mpi. Cresyl Violet (Nissl) counterstain. Scale bar, 10 μm. (n = 4 mice per group). Box plots show median, 25th and 75th percentiles, minimum and maximum values. **P < 0.01.
