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Synapses go nucle(ol)ar

Nature Neuroscience volume 10, pages 399–400 (2007)Cite this article

Jordan and colleagues report that activity causes the shuttling of a synaptic protein AIDA-1d from dendritic spines to the nucleus. This work sheds light on how nuclear protein synthesis is regulated in response to synaptic activity.

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Figure 1: AIDA-1, a PSD component, is cleaved into amino and carboxy portions following NMDA receptor activation.

Katie Ris

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Author notes

  1. Justin R. Fallon is at the Department of Neuroscience, Brown University, Box G-L, Sidney Frank Hall 358, 185 Meeting St., Providence, Rhode Island 02912, USA. justin_fallon@brown.edu

Authors and Affiliations

  1. Joel D. Richter is at the Program in Molecular Medicine, University of Massachusetts Medical School, 373 Plantation St., Suite 204, Worcester, Massachusetts 01605, USA.,

    Joel D Richter & Justin R Fallon

Authors
  1. Joel D Richter
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  2. Justin R Fallon
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The authors declare no competing financial interests.

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Richter, J., Fallon, J. Synapses go nucle(ol)ar. Nat Neurosci 10, 399–400 (2007). https://doi.org/10.1038/nn0407-399

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