New findings reveal that steroid hormones masculinize some aspects of the rat brain via prostaglandins. Blocking prostaglandin synthesis with drugs like aspirin can interfere with sexual differentiation of the brain and impair sexual behavior later in life.
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Erin Boyle
References
Phoenix, C.H., Goy, R.W., Gerall, A.A. & Young, W.C. Endocrinology 65, 369–382 (1959).
Amateau, S.K. & McCarthy, M.M. Nat. Neurosci. 7, 643–650 (2004).
Gorski, R.A., Harlan, R.E., Jacobson, C.D., Shryne, J.E. & Southam, A.M. J. Comp. Neurol. 193, 529–539 (1980).
Jordan, C.L. J. Neurobiol. 40, 434–445 (1999).
Amateau, S.K. & McCarthy, M.M. J. Neurosci. 22, 8586–8596 (2002).
Bezzi, P. et al. Nature 391, 281–285 (1998).
Cohen-Cory, S. Science 298, 770–776 (2002).
Montana, V., Ni, Y., Sunjara, V., Hua, X. & Parpura, V. J. Neurosci. 24, 2633–2642 (2004).
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Ottem, E., Zuloaga, D. & Breedlove, S. Brain gender: prostaglandins have their say. Nat Neurosci 7, 570–572 (2004). https://doi.org/10.1038/nn0604-570
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DOI: https://doi.org/10.1038/nn0604-570
