Contrary to many silica materials, certain types of mesoporous silica nanoparticles do not rupture red blood cells easily
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References
Slowing, I. I. Wu, C-W. Vivero-Escoto, J. L. & Lin, V.S-Y. Mesoporous silica nanoparticles for reducing haemolytic activity towards mammalian red blood cells. Small 10.1002/smll.200800926 (2008).
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Chun, A. Keep the red stuff in. Nature Nanotech (2008). https://doi.org/10.1038/nnano.2008.402
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DOI: https://doi.org/10.1038/nnano.2008.402