Figure 3
From: Defining molecular basis for longevity traits in natural yeast isolates
Selected phenotypes correlating with replicative lifespan. Levels of (a) asparagine, (b) glutamine, and (c) 2-octenoic acid negatively correlate with maximum replicative lifespan (Max RLS). Regression slope P values: (a) 0.014; (b) 0.042; and (c) 0.019. (d) Protein–protein interaction network of the top hits identified by the mean protein values. The interaction network is based on STRING database (evidence view). Genes without interacting partners are omitted. Selected pathways are indicated by colored rings. Most of the proteins here showed significant correlation to all four RLS measures. See Supplementary Table 2 for more details.
