Table 4 Analysis of the independent variants within the CETP region conditioned on the lead SNP for the CETP region as reported by the study by Teslovich et al.9 (rs3764261) in the combined analysis of all discovery and replication cohorts

From: Fine mapping the CETP region reveals a common intronic insertion associated to HDL-C

     

Unadjusted analysis

Adjusted analysis

Marker name

Chr

Position

EA

NEA

Freq

βa

S.e. β

P value

Freq

βa

S.e. β

P value

rs12920974

16

56,993,025

T

G

0.344

−1.880

0.074

9.91E−143

0.336

−0.278

0.076

2.82E−04

rs34065661

16

56,995,935

C

G

0.854

−9.333

0.520

6.02E−72

0.838

−4.368

0.550

1.94E−15

rs5817082

16

56,997,349

CA

C

0.360

−2.765

0.085

1.49E−231

0.351

−1.701

0.086

2.16E−86

rs4587963

16

56,997,369

A

T

0.351

−1.133

0.077

1.62E−48

0.339

0.309

0.079

8.81E−05

rs7499892

16

57,006,590

T

C

0.317

−3.275

0.082

2.90E−346

0.304

−2.205

0.083

5.14E−156

  1. Abbreviations: CETP, cholesteryl ester transfer protein; EA, effect allele for which the effect on HDL-C is estimated; Freq, the frequency of effect allele; SNP, single nucleotide polymorphism.
  2. aβ is the effect of the effect allele.
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