Figure 5
From: Deficiency of angiotensin-converting enzyme 2 causes deterioration of cognitive function
Effect of ACE2 deficiency on BDNF expression. (a) BDNF mRNA was detected using real-time RT-PCR as described in Materials and methods. Data are expressed as mean±s.e.m. (n=8 for each group). *P<0.05 versus WT mice. (b) BDNF protein was detected by western blot as described in Materials and methods. Values are expressed as mean±s.e.m. (n=14 for each group). ACE2, angiotensin-converting enzyme 2; BDNF, brain-derived neurotrophic factor; RT-PCR, reverse transcriptase polymerase chain reaction; WT, wild type.
