Table 3 Clinicopathological characteristics and treatment regimens of the 3,987 patients in the BCCA cohort

From: αB-crystallin expression in breast cancer is associated with brain metastasis

 

N

%

Age (years)

  

 <40

294

7

 40–49

843

21

 50–65

1,423

36

 >65

1,427

36

Grade

 1

209

6

 2

1,562

41

 3

2,037

54

 NA

179

 

Menstrual status at referral

 Pre-menopausal

1,178

30

 Post-menopausal

2,717

70

 NA

92

 

Nodal status

 Negative

2,265

57

 Positive

1,714

43

 NA

8

 

Lymphovascular invasion

 Negative

2,105

55

 Positive

1,709

45

 NA

173

 

Tumor size (cm)

 ≤2

2,077

52

 2–5

1,665

42

 >5

221

6

 NA

24

 

Initial Adjuvant Systemic Therapy

 None

1,676

42

 Tamoxifen only

1,274

32

 Chemotherapy only (AC, FAC or CMF)

725

18

 Tamoxifen and chemotherapy

296

8

 Other

16

 
  1. Abbreviations: AC, adriamycin and cyclophosphamide; BCCA, British Columbia Cancer Agency; CMF, cyclophosphamide, methotrexate, and 5-fluorouracil; FAC, 5-fluorouracil and AC; NA, not available.