Table 2 Association results of genes with P⩽0.01 with overall, ER+, and ER− breast cancer risk in the AMBER Consortium
Gene | Total number of SNPs | Effective number of SNPs | P value | ||
|---|---|---|---|---|---|
All cases | ER + | ER − | |||
BAIAP2 | 652 | 258 | 3.0×10−3 | 1.0×10−3 | 0.039 |
CALM2 | 158 | 72 | 9.0×10−3 | 0.018 | 0.39 |
CSNK2A1 | 400 | 150 | 0.033 | 0.010 | 0.11 |
BRAF | 812 | 106 | 0.013 | 0.40 | 3.0×10−3 |
BAD | 51 | 26 | 0.049 | 0.32 | 4.9×10−3 |
MAPK3 | 24 | 11 | 0.39 | 0.88 | 9.0×10−3 |