Figure 5

Schematic of the TCA cycle and the expression changes under microgravity. The enzymes indicated by blue symbols exhibited lower gene and/or protein expression in space-flown worms. Almost all enzymes (citrate synthase, aconitase, isocitrate dehydrogenase, succinate dehydrogenase, fumarase, malate dehydrogenase) participated in the TCA cycle showed lower expression.