Table 1 Analysis by colorimetric enzyme assays of mouse blood at completion (day 35) of study

From: Evaluation of rodent spaceflight in the NASA animal enclosure module for an extended operational period (up to 35 days)

Lipid profile

Vivarium

AEM

 

Mean

s.d.

N

Mean

s.d.

N

Cholesterol (mg/dl)

54.9

31.8

35

76.1

12.0

36

Triglyceride (mg/dl)

91.2

28.2

36

119.9

37.3

36

Chemical profile

 ALK phasphatase (IU/l)

103.5

18.6

35

87.4

19.1

35

 ALT (SGPT, IU/l)

25.9

36.7

36

26.0

9.8

36

 AST (SGOT, IU/l)

96.9

51.3

35

115.9

52.2

36

 CPK (IU/l)

293.0

235.5

36

313.2

202.9

36

 Albumin (g/dl)

2.8

0.3

35

2.7

0.1

36

 Total protein (g/dl)

4.5

0.5

35

4.5

0.2

36

 Globulin (g/dl)

1.7

0.2

35

1.8

0.1

36

 Total bilirubin (mg/dl)

0.2

0.1

36

0.2

0.1

36

 Direct bilirubin (mg/dl)

0.2

0.0

36

0.2

0.0

36

 BUN (mg/dl)

24.4

5.7

36

25.4

3.5

36

 Creatinine

0.0

0.0

35

0.0

0.0

36

 Glucose (mg/dl)

229.8

37.2

36

231.1

31.3

36

 Calcium (mg/dl)

7.5

1.0

35

7.7

0.5

36

 Phosphorus (mg/dl)

5.2

1.1

35

5.1

0.6

36

 TCO2 (bicarbonate)

12.5

3.3

35

10.2

2.8

36

 A/G ratio

1.6

0.1

35

1.5

0.1

36

 Indirect bilirubin

0.0

0.0

36

0.0

0.0

0

Basic CBC

 WBC (Ă—103/μl)

3.8

1.1

35

2.5

0.8

35

 RBC (Ă—106/μl)

9.0

0.4

35

9.1

0.3

35

 HGB (g/dl)

14.7

0.4

35

14.6

0.5

35

 HCT (%)

41.8

1.8

35

44.7

1.6

35

 MCV (fl)

46.5

0.7

35

48.9

0.9

35

 MCH (pg)

16.3

0.4

35

15.9

0.3

35

 MCHC (g/dl)

35.2

1.0

35

32.6

0.4

35

 NRBC (/100 WBC)

0.1

0.7

35

0.3

0.7

35

 Neutrophil SEG (%)

12.3

4.6

35

13.8

6.3

35

 Lymphocyte (%)

81.7

5.5

35

78.7

7.3

35

 Monocyte (%)

4.7

1.6

35

6.4

2.9

35

 Eosinophil (%)

1.2

0.7

35

1.1

0.6

35

 Basophil (%)

0.4

0.5

35

0.2

0.4

35

 ABS neutrophil SEG (1/μl)

443.7

143.3

35

323.6

140.8

35

 ABS lymphocyte (1/μl)

3,154.3

987.8

35

1,944.7

724.5

35

 ABS monocyte (1/μl)

177.5

73.4

35

159.0

100.9

35

 ABS eosinophil (1/μl)

45.4

36.1

35

25.9

13.9

35

 ABS basophil

15.9

19.8

35

3.3

7.8

35

  1. Abbreviations: ABS, absolute; AEM, Animal Enclosure Module; ALT, alanine aminotransferase; AST, aspartate aminotransferase; CBC, complete blood count; CPK, creatine phosphokinase; HCT, hematocrit; HGB, hemoglobin; MCH, mean corpuscular hemoglobin; MCHC, MCH concentration; MCV, mean corpuscular volume; NRBC, nucleated red blooc cells; RBC, red blood corpuscles; SEG, segmented neutrophils; SGPT, serum glutamic-pyruvic transaminase; SGOT, serum glutamic-oxaloacetic transaminase; WBC, white blood corpuscles.
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