Figure 5

Data from metabolomics analysis. Upper row; Cross-validated OPLS-DA scores for pairwise OPLS-DA models between control mice (black dots) and FN075 injected mice (blue dots) (P_1month=0.02, P_3months=0.03, P_6months=0.06; based on ANOVA of cross-validated models). Lower row; Cross-validated OPLS-DA scores for pairwise OPLS-DA models between; control mice (black dots) and inhibitor-injected mice (red dots) (P_1month=0.23, P_3months=0.17, P_6months=0.71; based on ANOVA of cross validated models). Each sample class is described by the average and 95% confidence interval. In all plots each symbol represents one serum sample described by the whole-measured metabolite profile.