Table 1 Differential features of ILD and COPD

From: Interstitial lung disease: raising the index of suspicion in primary care

 

ILD

COPD

Physical examination

 Inspiratory crackles21

✓

×

 Wheezing14

×

✓

 Finger clubbing 22

✓

×

Spirometry 16

 Reduction in TLC

✓

×

 Reduced FEV1/FVC ratio

×

✓

Response to bronchodilators

×

✓

Chest radiographs1

Show specific patterns of abnormality

Largely normal

  1. Abbreviations: COPD, chronic obstructive pulmonary disease; FEV1, forced expiratory volume in 1s; FVC, forced vital capacity; ILD, interstitial lung disease.
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