Table 3 Negative binomial regression of age, smoking status and various measures of baseline COPD severity with the number of hospital admissions and exacerbations in the 12-month follow-up in the OPC data set

From: Multi-component assessment of chronic obstructive pulmonary disease: an evaluation of the ADO and DOSE indices and the global obstructive lung disease categories in international primary care data sets

N=4400

Hospital admissions in the next 12 months

Exacerbations in the next 12 months

 

Incident rate ratio (95% confidence interval)

AIC

Incident rate ratio (95% confidence interval)

AIC

DOSE index

1.50 (1.33–1.68)

982

1.52 (1.46–1.57)

8,913

ADO index

1.23 (1.10–1.39)

1,013

1.16 (1.12–1.20)

9,352

Number of exacerbations in the 12 months before baseline

1.14 (1.09–1.18)

978

1.28 (1.26–1.31)

8,671

FEV1%

0.976 (0.966–0.986)

1,001

0.987 (0.985–0.990)

9,323

Smoking status:

 

1,013

 

9,414

Never

1.00

 

1.00

 

Ex

1.17 (0.63–2.16)

 

1.08 (0.88–1.32)

 

Current

0.47 (0.23–0.98)

 

1.00 (0.88–1.32)

 

MRC dyspnoea scale

1.38 (1.14–1.68)

1,015

1.28 (1.21–1.37)

9,351

Age

1.01 (0.99–1.03)

1,025

1.00 (0.99–1.00)

9,413

  1. Abbreviations: AIC, Akaike’s information criterion; FEV1%, forced expiratory volume in 1 s as a percentage of predicted.