Figure 3 | npj Primary Care Respiratory Medicine

Figure 3

From: Appropriate use of inhaled corticosteroids in COPD: the candidates for safe withdrawal

Figure 3

WISDOM: probability of moderate or severe exacerbations over 54 weeks in patients with severe-to-very-severe COPD (FEV1<50% predicted) and ⩾1 exacerbation in the year prior to screening.32 Hazard ratio is for ICS withdrawal versus ICS continuation. CI, confidence interval; ICS, inhaled corticosteroid. Reproduced from New England Journal of Medicine.61 Copyright © (2014) Massachusetts Medical Society. Reprinted with permission from Massachusetts Medical Society.

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