Figure 1 | npj Systems Biology and Applications

Figure 1

From: Network reconstruction and validation of the Snf1/AMPK pathway in baker’s yeast based on a comprehensive literature review

Figure 1

The Snf1 pathway and its components. The reaction graph depicts the pathway components of the NR1 network, and the different reactions they take part in (excluding the nuclear import and export reactions, and the nuclear pore complex mediating them). The SNF1 complex is regulated by kinases, phosphatases and other modifiers shown at the top. The transcriptional regulation is shown at the bottom. The coloured circles represent components and coloured edges represent different classes of reactions. The information in the reaction graph is only topological, and the edges cannot be interpreted in terms of information flow. However, most of them do carry information, as shown in the regulatory graph (Figure 2).

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