Table 1 Reactions with significant quantity changes on protein level between time points t₁ and t₈

Reaction ID	Name	Protein ID	Change	P-value	EC number
R_ACTPASE	Acylphosphatase	EF2401	0.452	0.0013	3.6.1.7
R_ADPT	Adenine phosphoribosyltransferase	EF1687	1.6662	0.0149	2.4.2.7
R_ADSS	Adenylosuccinate synthetase	EF0014	0.5674	0.0075	6.3.4.4
R_AICART	Phosphoribosylaminoimidazolecarboxamide formyltransferase	EF1778	0.41	0.0421	2.1.2.3
R_ASPK	Aspartate kinase	EF0368	0.4923	0.0202	2.7.2.4
R_CDD	Cytidine deaminase	EF0175	0.4768	0.0001	3.5.4.5
R_GAT1_EFA	Glycerol 3-phosphate acyltransferase	EF3112	1.5759	0.0379	2.3.1.15
R_GLUDy	Glutamate dehydrogenase	EF1415	0.609	0.0395	1.4.1.4
R_GLYK	Glycerol kinase	EF1929	0.5845	0.0448	2.7.1.30
R_IMPC	IMP cyclohydrolase	EF1778	0.41	0.0421	3.5.4.10
R_LDH1^a	Lactate dehydrogenase	EF0255	2.3418	0.0531	1.1.1.27
R_PDE1	3′5′-cyclic-nucleotide phosphodiesterase	EF0063	0.4704	0.0028	3.1.4.17
R_PDE2	3′5′-cyclic-nucleotide phosphodiesterase	EF0063	0.4704	0.0028	3.1.4.17
R_PDE3	3′5′-cyclic-nucleotide phosphodiesterase	EF0063	0.4704	0.0028	3.1.4.17
R_PDE4	3′5′-cyclic-nucleotide phosphodiesterase	EF0063	0.4704	0.0028	3.1.4.17
R_PDE5	3′5′-cyclic-nucleotide phosphodiesterase	EF0063	0.4704	0.0028	3.1.4.17
R_PFL	Formate C-acetyltransferase	EF1612	3.057	0.0001	2.3.1.54
R_PGL	6-Phosphogluconolactonase	EF1918	1.7277	0.0092	3.1.1.31
R_PPM2	Phosphopentomutase (deoxyribose)	EF0185	2.046	0.0156	5.4.2.7
R_PRFGS	Phosphoribosylformylglycinamidine synthase	EF1784	0.1896	0.0028	6.3.5.3
R_RHC	Ribosylhomocysteinase	EF1182	1.7792	0.0319	4.2.1.21
R_UDPG4E	UDPglucose 4-epimerase	EF1070	2.3293	0.0109	5.1.3.2

Abbreviation: EC, Enzyme Commission.
^a Lactate dehydrogenase missed the threshold by 0.03 but was included due to the metabolic data. A comprehensive list of the significant protein quantity changes for all time points can be found in the Supplementary Table S10.

Quick links

Search