Figure 3
From: Predictive model of thrombospondin-1 and vascular endothelial growth factor in breast tumor tissue
Sensitivity indices of model parameters. The extended Fourier Amplitude Sensitivity Test (eFAST) was used to estimate the variance in the model output with respect with variance in individual model inputs (first-order indices) and covariances in combinations of model inputs (total indices). The eFAST method was used to investigate the sensitivity to receptor numbers, secretion and degradation parameters, and kinetic parameters. The ‘ratio’ refers to the ratio of TSP1 secretion by the endothelial cells compared to the tumor cells.
