Figure 4

(a) Orbital frontal cortex (OFC) layer II somatostatin (SST) mRNA+ neuron density in OFC layer II (in situ hybridization). (b) SST mRNA expression in the white matter in human OFC. Quantitative PCR (qPCR) mRNA expression for (c) SST, (d) parvalbumin, (e) FAS receptor, and (f) TNFSF13 in schizophrenia (black) compared with control (gray) subjects in the OFC. Error bars represent s.e.m. *P<0.05; ***P<0.001.