Table 3 Vascular and metabolic parameters

From: Microvascular dysfunction in schizophrenia: a case–control study

 

Schizophrenia (N)

Control (N)

P-value

Total sample

51

51

 

Mean

s.d.

Mean

s.d.

 

Vascular parameters

 Velocity time integral (cm)

104.9

33.0

129.1

33.8

<0.001

 Flow-mediated dilation (%)

7.1

4.8

7.1

3.8

0.933

 Pulse arterial tonometry

1.94

0.58

1.92

0.43

0.862

Baseline diameter of brachial artery (cm)

4.06

0.671

3.97

0.636

0.488

Metabolic parameters

 Total cholesterol (mmol/l)

4.72

0.82

4.37

0.73

0.028

 HDL-cholesterol (mmol/l)

1.15

0.30

1.49

0.46

<0.001

 LDL-cholesterol (mmol/l)

2.71

0.79

2.38

0.69

0.033

 Glucose fasting (mmol/l)

5.24

1.07

4.79

0.36

0.007

 Hemoglobin A1c (%)

5.65

0.29

5.39

0.28

<0.001

 Hemoglobin (g/l)

148

14

150

13

0.415

 

Median

25 th , 75 th percentile

Median

25 th , 75 th percentile

 

Creatinine (μmol/l)

77

21

77

15

0.890

High-sensitivity C-reactive protein (mg/l)

1.50

(0.70, 3.22)

0.80

(0.40, 1.22)

0.003

Insulin (pmol/l)

58.9

(42.9, 96.4)

34.8

(22.6, 42.6)

<0.001

HOMA-IR

1.82

(1.25, 3.36)

1.04

(0.66, 1.34)

<0.001

Triglycerides (mmol/l)

1.61

(1.11, 2.57)

0.88

(0.67, 1.21)

<0.001

  1. Abbreviations: HDL, high-density lipoprotein; HOMA-IR, homeostatic model assessment-insulin resistance; LDL, high-density lipoprotein.