Table 3 Behavioral response times to the incongruent Stroop condition and correlation to glutamate and glutamine concentrations and percent changes during those trials

Trial	Subject group	Response time (s)	Correlations
			Glu	P	ΔGlu	P	Gln	P	ΔGln	P
Stroop1	HC	0.92±0.16	−0.42	0.077	0.04	0.446	−0.45	0.081	−0.34	0.151
	MDD	0.95±0.12	−0.37	0.08	−0.30	0.126	−0.41	0.063	−0.67	0.003
	SZ	1.03±0.08	−0.35	0.099	−0.23	0.207	−0.50	0.033	−0.65	0.006
	All	0.97±0.13	−0.32	0.017	−0.15	0.166	−0.40	0.005	−0.33	0.019
Stroop2	HC	0.84±0.15	−0.39	0.107	0.28	0.178	−0.60	0.026	−0.58	0.031
	MDD	0.89±0.13	−0.30	0.133	−0.28	0.144	−0.20	0.249	−0.45	0.055
	SZ	0.93±0.13	0.38	0.083	0.14	0.309	−0.17	0.287	−0.20	0.244
	All	0.89±0.14	−0.08	0.313	0.04	0.387	−0.28	0.040	−0.28	0.045

Abbreviations: All, the combination of all the participants across groups; HC, healthy control; MDD, major depressive disorder; SZ, schizophrenia.
Glu represents glutamate correlation coefficient (Pearson r) with response times. ΔGlu represents the normalized glutamate concentration change. Gln represents glutamine correlation coefficient (Pearson r) with response times. ΔGln represents the normalized glutamine concentration change correlation coefficient (Pearson r) with response times. P represents probability that the correlation is due to chance (alpha=0.05/4 (Bonferroni corrected), one-tailed), values in bold indicate statistical significance.

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