Table 1 Measures of cognition, clinical symptoms, quality of life, and hippocampal volume at baseline, after 12 weeks intervention and at 18-month follow-up

From: Aerobic exercise and yoga improve neurocognitive function in women with early psychosis

 

Yoga group

Aerobic exercise group

Waitlist control group

 

Baseline

12 weeks

18 months

Baseline

12 weeks

18 months

Baseline

12 weeks

18 months

Cognition

 Sample size

45

38

23

40

31

22

39

33

18

 HKLLT-acquisition, mean (s.d.)

23.4 (6.1)

30.1 (6.6)

28.1 (6.3)

22.7 (8.0)

29.1 (8.2)

28.9 (8.2)

22.7 (7.6)

24.7 (8.1)

29.6 (6.7)

 HKLLT-retention, mean (s.d.)

15.2 (6.1)

19.8 (6.0)

18.4 (6.5)

15.6 (5.4)

21.3 (7.1)

19.6 (7.5)

14.5 (7.0)

16.5 (7.2)

19.1 (6.9)

 Digit span forwards test, mean (s.d.)

11.7 (2.3)

12.7 (1.8)

12.4 (2.0)

12.1 (1.8)

13.1 (1.2)

12.8 (1.1)

12.3 (1.8)

12.3 (2.1)

13.4 (0.9)

 Digit span backwards test, mean (s.d.)

7.0 (3.0)

8.7 (3.0)

8.5 (3.4)

6.7 (2.5)

9.5 (3.0)

9.4 (3.3)

7.7 (3.3)

7.3 (2.7)

9.2 (3.0)

 Letter cancellation test, Q score, mean (s.d.)

0.76 (0.14)

0.85 (0.18)

0.82 (0.15)

0.72 (0.21)

0.78 (0.19)

0.79 (0.21)

0.75 (0.15)

0.73 (0.17)

0.84 (0.13)

 Stroop test congruent condition, correct items mean (s.d.)

110.3 (2.6)

111.1 (1.8)

110.9 (1.1)

110.0 (2.7)

110.9 (2.5)

110.6 (1.7)

110.5 (1.6)

110.4 (1.5)

111.4 (1.0)

 Stroop test incongruent condition, corrected items, mean (s.d.)

105.7 (4.5)

108.2 (3.4)

108.8 (3.3)

105.4 (5.6)

106.9 (4.6)

107.5 (3.6)

103.3 (8.2)

105.5 (6.1)

108.7 (2.8)

Clinical symptoms

 Sample size

45

38

23

40

31

22

39

33

18

 PANSS total, mean (s.d.)

47.5 (15.4)

37.6 (9.3)

39.1 (9.7)

46.4 (15.9)

39.1 (10.9)

35.6 (6.3)

45.9 (15.3)

49.4 (15.8)

42.2 (10.7)

 PANSS positive, mean (s.d.)

10.2 (3.7)

8.7 (2.7)

8.6 (2.2)

9.5 (4.5)

8.3 (2.4)

7.8 (1.5)

9.9 (3.8)

10.1 (3.5)

9.9 (4.4)

 PANSS negative, mean (s.d.)

10.8 (4.2)

8.5 (2.7)

8.4 (3.1)

10.9 (5.6)

9.5 (3.7)

8.1 (2.1)

11.2 (4.1)

12.7 (5.1)

9.6 (3.8)

 PANSS general, mean (s.d.)

26.6 (9.3)

20.4 (5.5)

22.1 (7.0)

26.0 (9.2)

21.3 (6.7)

19.6 (3.9)

24.8 (9.2)

26.6 (9.6)

22.7 (5.2)

 CDS total, mean (s.d.)

4.1 (4.2)

1.7 (2.4)

2.7 (3.4)

3.3 (4.0)

1.6 (2.3)

1.7 (1.9)

3.7 (4.7)

4.3 (4.3)

1.8 (1.7)

Hippocampal volume (mm3)

 Sample size

25

20

 

28

17

 

20

13

 

 Left HPC, mean (s.d.)

3,511 (290)

3,459 (259)

 

3,461 (385)

3,475 (428)

 

3,533 (314)

3,530 (272)

 

 Right HPC, mean (s.d.)

3,726 (309)

3,667 (262)

 

3,645 (373)

3,638 (378)

 

3,726 (326)

3,724 (310)

 

 Total HPC, mean (s.d.)

7,237 (589)

7,126 (506)

 

7,106 (741)

7,113 (793)

 

7,259 (629)

7,254 (560)

 

Quality of Life

 Sample size

44

38

 

40

31

 

38

32

 

 Physical health, mean (s.d.)

64.1 (16.9)

71.4 (18.0)

 

64.5 (17.2)

75.0 (17.4)

 

69.4 (17.4)

68.8 (19.5)

 

 Psychological health, mean (s.d.)

57.2 (22.0)

67.8 (21.6)

 

60.0 (19.2)

73.1 (29.6)

 

60.7 (20.0)

57.2 (23.6)

 

Body perception

 Sample size

44

38

23

40

31

22

38

32

18

 FRS, mean (s.d.)

1.8 (1.2)

1.8 (1.4)

2.0 (1.1)

1.5 (1.0)

1.5 (1.2)

1.6 (1.3)

1.6 (1.4)

1.3 (1.3)

1.5 (1.3)

Drug adherence

 Sample size

41

37

23

37

31

22

35

32

18

 MCR, mean (s.d.)

6.0 (0.7)

6.0 (0.5)

5.9 (0.4)

5.9 (0.8)

6.1 (0.7)

6.0 (0.8)

5.9 (0.5)

6.0 (0.7)

5.9 (0.3)

Fitness

 Sample size

38

23

 

35

18

 

23

11

 

 VO2 max

25.3 (6.2)

25.9 (5.5)

 

27.1 (5.4)

29.2 (5.9)

 

26.1 (5.0)

26.0 (5.2)

 
  1. Abbreviations: CDS, calgary depression scale; FRS, figure rating scale; HKLLT, Hong Kong list learning test; HPC, hippocampus; MCR, medication compliance rating; PANSS, positive and negative syndrome scale.