Figure 1 | npj Schizophrenia

Figure 1

From: Biological pathways modulated by antipsychotics in the blood plasma of schizophrenia patients and their association to a clinical response

Figure 1

(a) Biological processes represented by all 985 plasma proteins identified through the shotgun mass spectrometry profiling approach; (b) western blot validation of the mass spectrometry findings for coronin-2A, which showed increased levels in responders and decreased levels in non-responders; (c) Biological pathways affected by antipsychotics in responders (blue bars) and non-responders (red bars); (d) Percentage of proteins increased in responders (blue), decreased in responders (red), increased in non-responders (green) and decreased in non-responders (purple) in the same biological pathways shown in part (c). For (c and d) the y axis represents the percentage of differentially expressed proteins associated to those processes and a star indicates significant differences of the protein constituents (c) or directional changes (d) within a pathway.

Back to article page