Table 2 Demographics and clinical characteristics for the prospective meta-analysis

From: Alterations in the hippocampus and thalamus in individuals at high risk for psychosis

Characteristics

Clinical high risk (n=91)

Healthy controls (n=64)

Statistics

 

Gender M/F (%male)

59/32 (64%)

33/31 (52%)

χ2=2.22

P=0.14

Mean age in years (s.d.)

23.70 (5.11)

25.50 (4.76)

t=2.24

P=0.03*

Handedness r/l (%left)

84/7 (8%)

57/7 (11%)

χ2=0.17

P=0.68

Years of education (s.d.)

12.90 (3.00)

14.89 (2.97)

t=3.87

P=0.0002*

IQ (s.d.)

108 (15.31)

112 (14.38)

t=1.76

P=0.08

Negative cluster (s.d.)

6.54 (3.17)

3.00 (0)

t=−10.62

P<0.0001*

Positive cluster (s.d.)

9.02 (3.52)

4.00 (0)

t=−13.53

P<0.0001*

GAF (s.d.)

61.05 (14.83)

88.08 (4.15)

t=15.19

P<0.0001*

Scanner ZH1/ZH2/BS

16/15/60

5/35/24

χ2=25.25

P<0.0001*

Antidepressants no/yes

59/32

64/0

χ2=26.25

P<0.0001*

Antipsychotics no/yes

84/7

64/0

χ2=3.53

P=0.06

  1. Abbreviations: F, female; GAF, global functioning; IQ, intelligent quotient; l, left; M, male; r, right; *, significant findings.
  2. Positive symptom cluster=either sum of Suspiciousness, Hallucinations, Unusual Thought Content and Conceptual Disorganisation (BPRS9, BPRS10, BPRS11, BPRS15 in Basel and PANSS P2, PANSS P3, PANSS P6, PANSS G9 in Zurich).
  3. Negative symptom cluster=either sum of Blunted Affect, Emotional Withdrawal and Motor Retardation (BPRS16, BPRS17, BPRS18 in Basel and PANSS N1, PANSS N2, PANSS G7 in Zurich).
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