Figure 5 | npj Vaccines

Figure 5

From: Intradermal immunisation using the TLR3-ligand Poly (I:C) as adjuvant induces mucosal antibody responses and protects against genital HSV-2 infection

Figure 5

HIV-1 gp140-specific IgG and IgA responses induced via ID route compared with those induced via s.c. and IN routes. Gp140-specific IgG (top panels) and IgA (bottom panels) were titrated in serum (a), vaginal fluids (b) and fecal extracts (c) of mice at various time points after the last immunisation with gp140 plus Poly(I:C) via either the ID (black squares), s.c. (white squares) or IN (black triangles) route. Results are expressed as mean+s.e.m. of Ab titres and are representative of one out of two experiments using 6 mice per group. Statistical analyses were performed using the two-way analysis of variance (ANOVA) test and Bonferroni’s multiple comparisons.

Back to article page