Figure 1
From: Maternal Behavior is Impaired in Female Mice Lacking Type 3 Adenylyl Cyclase
Pup retrieval is impaired in virgin AC3−/− mice. (a) The retrieval latencies of three pups on the first test day of virgin female AC3+/+ and AC3−/− mice are shown. There were significant differences between AC3+/+ (n=10) and AC3−/− (n=10) mice in the retrieval latency of the first, second, and third pups (p<0.001 for each pair). Data are represented as means±SEM. (b) The third pup retrieval latency for virgin female AC3+/+ and AC3−/− mice on 4 consecutive days is reported. The retrieval latency for the third pup for each day (p<0.001 for each pair) was significantly different between AC3+/+ (n=10) and AC3−/− females (n=10). The retrieval latency of AC3+/+ mice, but not AC3−/− mice decreased with repeated tests. Data are represented as means±SEM. **p<0.001. If an animal did not complete this behavior within 10 min the test was terminated, resulting in a latency of 600 s for any behaviors not yet observed.
