Figure 2
From: Maternal Behavior is Impaired in Female Mice Lacking Type 3 Adenylyl Cyclase
Nest building and pup retrieval are impaired in recently postpartum AC3−/− females. (a and b) Representative nests and pup distribution for AC3+/+ and AC3−/− dams. Pictures were photographed ∼6 h following parturition. (c) The pup retrieval latencies of the first day following partition (P0) in AC3+/+ and AC3−/− dams are reported. There were significant differences between AC3+/+ (n=11) and AC3−/− (n=9) mice in the retrieval latency for the first, second, and third pups (p<0.001 for each pairs). Data are represented as means±SEM. (d) The retrieval latency of the third pup for AC3+/+ and AC3−/− dams on the 4 consecutive days following partition are shown. There were significant differences between AC3+/+ (n=11) and AC3−/− (n=9) dams for the retrieval latency of the third pup on each day (p<0.001 for each pairs). Data are represented as means±SEM. **p<0.001. If an animal did not complete this behavior within 10 min the test was terminated, resulting in a latency of 600 s for any behaviors not yet observed.
