Figure 9 | Neuropsychopharmacology

Figure 9

From: Synaptic and Morphological Neuroadaptations in the Putamen Associated with Long-Term, Relapsing Alcohol Drinking in Primates

Figure 9

Chronic EtOH exposure with imposed abstinence decreases the frequency and amplitude of mIPSCs in MSNs of the monkey putamen. (a and b) Representative mIPSCs recorded from MSNs in slices obtained from control (panel a) and EtOH (panel b) monkeys. (c–e) The average (panel c), cumulative distribution (panel d), and relationship with blood EtOH concentration (panel e) of mIPSC interevent interval (IEI) measured in control (black) and EtOH (gray) monkeys. (f–h) The average amplitude (f), area (g), and rise and decay times (h) of mIPSCs measured in MSNs of control and EtOH monkeys. *Statistically significant differences from control at P<0.05.

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