Figure 5
Effects of mineralocorticoid receptor (MR) antagonist (RU-28318) administered into the dorsal hippocampus 15 min before acute stress on delayed alternation rates. Behavioral test session occurred either 15 or 60 min after stress. Control groups were animals receiving vehicle only, followed or not by acute stress. The administration of the MR antagonist at the dose of 20 μg/ml blocked the stress-induced impairment on alternation rates 15 min but not 60 min after stress delivery. Comparisons to vehicle stressed animals: **p<0.01; ***p<0.001; chance level: 50 %.
