Table 3 Haplotype Analysis of the RELA Gene Between Patients and Controls
From: Variants of the RELA Gene are Associated with Schizophrenia and their Startle Responses
Haplotype a | Frequency | Individual p (χ2) | Global p (χ2) | |
|---|---|---|---|---|
Patients | Controls | |||
SNP1-SNP2 | 0.0019 (12.13) | |||
1–0 | 0.43 | 0.47 | 0.012 (6.88) | |
0–0 | 0.45 | 0.40 | 0.00060 (12.10) | |
0–1 | 0.12 | 0.13 | 0.19 (1.59) | |
SNP2-SNP3 | 0.00080 (13.24) | |||
0–1 | 0.44 | 0.48 | 0.0053 (8.03) | |
0–0 | 0.45 | 0.40 | 0.00030 (13.24) | |
1–0 | 0.12 | 0.13 | 0.23 (1.38) | |
SNP3-SNP4 | 0.00040 (15.14) | |||
1–0 | 0.43 | 0.48 | 0.0031 (9.19) | |
0–1 | 0.45 | 0.40 | 0.00006 (15.14) | |
0–0 | 0.12 | 0.13 | 0.21 (1.56) | |
SNP1-SNP2-SNP3 | 0.0022 (12.03) | |||
1–0–1 | 0.43 | 0.47 | 0.0071 (7.07) | |
0–0–0 | 0.45 | 0.40 | 0.00070 (12.02) | |
0–1–0 | 0.12 | 0.13 | 0.22 (1.40) | |
SNP2-SNP3-SNP4 | 0.00090 (13.66) | |||
0–1–0 | 0.44 | 0.48 | 0.0028 (8.68) | |
0–0–1 | 0.45 | 0.40 | 0.00040 (13.65) | |
1–0–0 | 0.11 | 0.12 | 0.26 (1.20) | |
SNP1-SNP2-SNP3-SNP4 | 0.0022 (13.11) | |||
1–0–1–0 | 0.43 | 0.47 | 0.0058 (8.32) | |
0–0–0–1 | 0.45 | 0.40 | 0.00060 (13.11) | |
0–1–0–0 | 0.12 | 0.12 | 0.27 (1.17) | |
