Figure 5
Effects of GSK1521498 and naltrexone (NTX) on binge eating. On the top, effect of GSK15121498 on 10-min access to chow (a), 10-min access to chow or chocolate (b), access to chow in home-cage, and after the experimental session (c). Values represent the averaged caloric intakes (kcal) (±SEM) in chow/chow-fed animals (n=5 females, black bars) and in chow/chocolate-fed rats (n=6 females, white bars). *p<0.05, **p<0.01 compared with vehicle-treated chow/chocolate-fed animals; ##p<0.01 compared with vehicle-treated chow/chow-fed animals. On the bottom, effect of NTX on 10-min access to chow (d), 10-min access to chow or chocolate (e), access to chow in home-cage, and after the experimental session (f). Values represent the averaged caloric intakes (kcal) (±SEM) in chow/chow-fed animals (n=5, black bars) and in chow/chocolate-fed rats (n=6, white bars). *p<0.05, **p<0.01 compared with vehicle-treated chow/chocolate-fed animals.
