Figure 1 | Neuropsychopharmacology

Figure 1

From: Withdrawal-Associated Increases and Decreases in Functional Neural Connectivity Associated with Altered Emotional Regulation in Alcoholism

Figure 1

Brain regions identified with a main effect of group ((a) yellow) or a significant three-way interaction ((b) yellow). Clusters are shown at an uncorrected voxel p-value of 0.001, with a minimum cluster size of 50 voxels. Primary motor cortex and orbitofrontal cortex (OFC) survived FWE corrections; insula was thresholded following correction for multiple comparisons on the basis of spatial extent. Sublenticular extended amygdala (SLEA) was identified based on region of interest analysis. Bar graphs depict changes of BOLD signal (mean±SEM) for the main effect of group (c) and the interaction involving group (d, e). MDTx, multiply detoxified; SDTx, singly detoxified.

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