Figure 2 | Neuropsychopharmacology

Figure 2

From: Deficiency of Schnurri-2, an MHC Enhancer Binding Protein, Induces Mild Chronic Inflammation in the Brain and Confers Molecular, Neuronal, and Behavioral Phenotypes Related to Schizophrenia

Figure 2

Comparison of gene expression profiles between Shn-2 KO mice and individuals with schizophrenia. (a) Venn diagram of genes differentially expressed in the medial prefrontal cortex (mPFC) of Shn-2 KO mice and Brodmann area (BA) 10 of postmortem schizophrenia brain (Schizo.). (b) P-values of overlap between Shn-2 KO mouse and schizophrenia data sets. (c) Scatter plot of gene expression fold change values in Shn-2 KO mice and schizophrenia. (d) Genes differentially expressed in both Shn-2 KO mice and schizophrenia. Red indicates gene upregulation and blue indicates downregulation in both Shn-2 KO mice and schizophrenia. The top 40 genes are included.

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