Table 1 Summary of the Experimental Design for the Five Experiments A through E
A | Surgery | Training Cocaine Cue lights ON Sessions 1–15 | Progressive responding Cocaine Session 16 | Cues-OFF extinction Saline Cue lights OFF Sessions 17–31 | Cue-induced reinstatement Saline Cue lights ON Session 32 |
B | Surgery | Training Cocaine Cue lights ON Sessions 1–15 | Progressive responding cocaine session 16 | Cues-ON extinction Saline Cue lights ON Sessions 17–31 | |
C | Surgery | Training Cocaine Cue lights ON Sessions 1–9 | Dose response Cocaine (dose order: 1, 0.1, 0.032, 0.32, 0.01, 3.2 mg/kg) Cue lights ON Sessions 10–21 | ||
D | No surgery | Stimulus light sessions No reward Cue lights ON Sessions 1–6 | |||
E | No surgery | Training Sucrose Cue lights ON Sessions 1–15 | Cues-ON extinction No reward Cue lights ON Sessions 16–30 |
