Figure 4 | Neuropsychopharmacology

Figure 4

From: Melanocortin 3 Receptor Signaling in Midbrain Dopamine Neurons Increases the Motivation for Food Reward

Figure 4

Intra-VTA MC3R stimulation increases motivation but not free feeding of sucrose. Effects of intra-VTA injections of γMSH on ALPs (a), rewards earned (b), ILPs (c), sucrose free-intake (d), and 24 h chow intake (e) (n=7–9). Effects of intra-VTA injections of αMSH on ALPs (f), rewards earned (g), and ILPs (h) (n=9). Effects of α-flupenthiixol (FLU) pretreatment on the number of ALPs (i), rewards earned (j), and ILPs (k) following intra-VTA γMSH infusion (n=21). One-way ANOVA, *p<0.05 **p<0.01, ***p<0.001 compared with saline condition.

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