Figure 1
From: Diversity of Dopaminergic Neural Circuits in Response to Drug Exposure

In vivo firing characteristics of VTA DA neurons. Active VTA DA neurons transition between two states of firing modes in vivo: (a) low-frequency tonic, single-spike firing and (b) high-frequency burst firing (inset shows expanded view of burst with onset occurring when two spikes fire within <80 ms and termination ending after >160 ms of silence). VTA DA neurons have a waveform shape under filter conditions. (c) Demonstration of a single recorded VTA DA neuron under three different filters used in electrophysiology. DA, dopamine; VTA, ventral tegmental area.