Figure 1
Genetic variation in the repeat upstream region of the marmoset SLC6A4 gene and its association with gene expression levels. (a) Schematic representation of the marmoset SLC6A4 promoter region showing 32 repeats. Third, fourth, and 23rd repeats containing the double and the two single-nucleotide polymorphisms, respectively, are shaded in grey. Representative examples of electropherograms of the most frequent haplotypes AC/C/G and CT/T/C are shown. (b) Relative expression values are shown (mean±SEM). One-way ANOVA F(2,32)=11.40, p<0.001 followed by post hoc LSD: AC/C/G vs CT/T/C p<0.001 (***), CT/T/C vs AC/C/G&CT/T/C p=0.020 (**), AC/C/G vs AC/C/G&CT/T/C p=0.047 (*).
