Figure 2
Adolescent CUS increases anxiety-like behaviors in adulthood. (a) Male and female mice exposed to adolescent CUS (S) buried more marbles in the MB task in adulthood than nonstressed (NS) control animals (*P<0.05). Bars represent number of marbles buried±SEM. Sample sizes are reported in the figure. (b) There is no difference in number of marbles buried between animals exposed to adult CUS and nonstressed control animals later in adulthood. (c) Male and female mice exposed to adolescent CUS spend less time in the open arm of the EZM as compared with NS controls (*P<0.05). Female mice spent less time in the open arm of the EZM regardless of adolescent stress exposure compared with male mice (##P<0.01). Bars represent time spent in the open arm of the EZM in seconds±SEM. (d) There is no difference in the amount of time spent in the open of the EZM in male and female mice exposed to adult CUS compared with nonstressed controls.
