Figure 3
Adolescent CUS decreases acoustic startle response in male mice in adulthood. (a) Exposure to adolescent CUS decreases startle amplitude at high dB tones in male adult mice compared with nonstressed controls (*P<0.05). Values are plotted as startle amplitude±SEM. Sample sizes of each condition are reported in the figure. The lowest dB SPL and three highest db SPL tones are shown. Multiple comparisons revealed a significant difference between adolescent male no stress and adolescent male stress at 120 dB SPL (#P<0.001). Female mice exposed to adolescent CUS showed no difference in startle response compared with nonstressed controls. (b) Male and female mice exposed to adult CUS showed no difference in startle response compared with nonstressed controls. Additional statistical analysis showed no significant differences between sexes at any dB examined.
