Figure 2
From: Decreased Brain pH as a Shared Endophenotype of Psychiatric Disorders
Lower pH and increased lactate levels in the brains of mouse models of psychiatric disorders. Bar graphs of pH (a), lactate levels (b), pyruvate levels (d), glucose levels (e), and ADP/ATP ratio (f) in the brains of Shn2 KO, Cn KO, Nrgn KO, Camk2a HKO, and Chd8 HKO mice and their corresponding controls (mean±SEM). Each plot represents individual mouse values. (c) Scatter plot showing correlations between pH and lactate levels in the mouse brain. Asterisks indicate statistically significant differences between controls and mutants after Bonferroni–Holm correction (*P<0.05, **P<0.01). ADP, adenosine diphosphate; ATP, adenosine triphosphate.
