Table 3 Adverse Events with an Incidence of ⩾5% in at Least One Treatment Arm
Placebo ( n =63) | Basimglurant 0.5 mg ( n =58) | Basimglurant 1.5 mg ( n =62) | |
---|---|---|---|
Overall total number of AEs | 112 | 96 | 155 |
Total patients with at least one AE, n (%) | 40 (63.5%) | 37 (63.8%) | 45 (72.6%) |
Nasopharyngitis | 11 (17.5%) | 9 (15.5%) | 6 (9.7%) |
Headache | 10 (15.9%) | 4 (6.9%) | 10 (16.1%) |
Vomiting | 5 (7.9%) | 3 (5.2%) | 7 (11.3%) |
Upper respiratory tract infection | 4 (6.3%) | 1 (1.7%) | 6 (9.7%) |
Anxiety | 1 (1.6%) | 2 (3.4%) | 6 (9.7%) |
Aggression | 1 (1.6%) | 5 (8.6%) | 5 (8.1%) |
Insomnia | 1 (1.6%) | 0 | 5 (8.1%) |
Diarrhea | 3 (4.8%) | 4 (6.9%) | 2 (3.2%) |
Upper abdominal pain | 4 (6.3%) | 2 (3.4%) | 0 |
Agitation | 2 (3.2%) | 0 | 4 (6.5%) |
Dizziness | 1 (1.6%) | 1 (1.7%) | 4 (6.5%) |
Irritability | 1 (1.6%) | 3 (5.2%) | 3 (4.8%) |