Abstract
According to the "RNA World Hypothesis" the first self replicating molecule formed from the prebiotic chemicals is the ribozyme. A model compartmentalized self replicating system for ribozyme polymerases is designed and used to improve activity, fidelity and generality of the enzyme.
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Khan, I., Akktar, M. & Khan, A. In vitro Evolution and Engineering for Improved Ribozyme Polymerase Production. Nat Prec (2011). https://doi.org/10.1038/npre.2011.6064.1
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DOI: https://doi.org/10.1038/npre.2011.6064.1
