Abstract
The possible impact of hydrophobic lectin nanoparticles on the prognosis and progression of Alzheimer's disease (AD) and cancers was investigated by Visual Molecular Dynamics (VMD) computer modeling programs available from the Beckmann Advanced Research Institute at the University of Illinois at Urbana. Our results indicate the possibility of impeding pathological aggregation of certain proteins such as modified tau- or beta-amyloid that are currently being considered as possible causes of Alzheimer's disease. VMD programs serve as useful tools for investigation hydrophobic protein aggregation that may play a role in aging of human populations.
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Baianu, I., Charles, M. & Prisecaru, V. Visual Molecular Dynamics Investigations of the Impact of Hydrophobic Nanoparticles on Prognosis of Alzheimer’s Disease and Cancers . Nat Prec (2012). https://doi.org/10.1038/npre.2012.7111.2
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DOI: https://doi.org/10.1038/npre.2012.7111.2
Keywords
- Visual Molecular Dynamics (VMD)
- computer modeling applications in Nanomedicine
- ;potential medical applications of Lectin nanoparticles
- VMD applications in Nanomedicine
- Nuclear Magnetic Resonance (NMR)
- MRI/ MRM; PET scanning
- Prognosis of Alzheimer's Disease (AD)
- hydrophobic protein nanoparticles
- Molecular Dynamics (VMD)investigations
