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Interventional cardiology

Absorbable scaffolds noninferior to metallic stents at 1 year

Nature Reviews Cardiology volume 12, page 622 (2015)Cite this article

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In a randomized trial conducted in Japan, a drug-eluting bioresorbable vascular scaffold (BVS) has shown medium-term noninferiority to a metallic drug-eluting stent (DES) in both clinical and angiographic outcomes for percutaneous coronary intervention (PCI) in patients with coronary artery disease (CAD).

BVSs provide medium-term physical support and antiproliferative-drug delivery for treatment of vascular stenosis. Unlike traditional metallic stents, BVSs are eventually absorbed, and evidence suggests they are associated with favourable vascular responses in the long term. However, the short-term and medium-term safety and efficacy profiles of these scaffolds, although important, are currently undefined.

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References

  1. Kimura, T. et al. A randomized trial evaluating everolimus-eluting Absorb bioresorbable scaffolds vs. everolimus-eluting metallic stents in patients with coronary artery disease: ABSORB Japan. Eur. Heart J. 10.1093/eurheartj/ehv435

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  1. Robert Phillips
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Phillips, R. Absorbable scaffolds noninferior to metallic stents at 1 year. Nat Rev Cardiol 12, 622 (2015). https://doi.org/10.1038/nrcardio.2015.145

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  • DOI: https://doi.org/10.1038/nrcardio.2015.145

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