Table 2 Expandable progenitors with immortalization
From: Expandable progenitors from induced pluripotent stem cells
Expandable progenitors | Transduction for immortalization | Starting cells | Final products |
|---|---|---|---|
Expandable cardiac progenitor cells7 | MYC (doxycycline-inducible) | hPSCs | • Cardiomyocytes • Smooth muscle cells • Endothelial cells |
Immortalized megakaryocyte progenitor cell lines8 | MYC, BMI1, BCL2L1 (doxycycline-inducible) | hPSCs | Platelets |
Immortalized erythrocyte progenitor cells9 | MYC, BCL2L1 (doxycycline-inducible) | hPSCs | Erythrocytes |
hiPSC-derived erythroid progenitor cells10 | HPV16-E6/E7 (doxycycline-inducible) | hiPSCs | Erythrocytes |
