Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • Research Highlight
  • Published:

Kidney cancer

Sunitinib has similar efficacy irrespective of age in mRCC

Nature Reviews Clinical Oncology volume 11, page 122 (2014)Cite this article

Subjects

Access through your institution
Buy or subscribe

An exploratory retrospective analysis of data from six key trials in patients with metastatic renal cell carcinoma (mRCC) has revealed that sunitinib has comparable efficacy regardless of patient age.

The analysis by Hutson and colleagues incorporated data from a total of 1,059 patients, with sunitinib used as the first-line agent in 783 or after IFN-α therapy in 276. These patients were stratified by age at baseline, with 857 aged <70 years and 202 aged ≥70 years (median of 57 years and 73 years, respectively). Importantly, proportions of patients in each age group and their baseline characteristics were similar, irrespective of treatment exposure.

This is a preview of subscription content, access via your institution

Access options

Access through your institution

Buy this article

  • Purchase on SpringerLink
  • Instant access to full article PDF
Buy now

Prices may be subject to local taxes which are calculated during checkout

References

  1. Hutson, T. E. et al. Efficacy and safety of sunitinib in elderly patients with metastatic renal cell carcinoma. Br. J. Cancer 10.1038/bjc.2013.832

Download references

Authors
  1. David Killock
    View author publications

    Search author on:PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

Killock, D. Sunitinib has similar efficacy irrespective of age in mRCC. Nat Rev Clin Oncol 11, 122 (2014). https://doi.org/10.1038/nrclinonc.2014.14

Download citation

  • Published:

  • Issue date:

  • DOI: https://doi.org/10.1038/nrclinonc.2014.14

This article is cited by

Search

Advanced search

Quick links

Nature Briefing: Cancer

Sign up for the Nature Briefing: Cancer newsletter — what matters in cancer research, free to your inbox weekly.

Get what matters in cancer research, free to your inbox weekly. Sign up for Nature Briefing: Cancer