Abstract
A wave of terminations of development programmes for cannabinoid receptor 1 blockers for obesity indicates the demise of a drug class that was once anticipated to yield blockbusters. Nevertheless, lessons learned might help salvage something for future such approaches.

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Jones, D. End of the line for cannabinoid receptor 1 as an anti-obesity target?. Nat Rev Drug Discov 7, 961–962 (2008). https://doi.org/10.1038/nrd2775
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DOI: https://doi.org/10.1038/nrd2775
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