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Mining for therapeutic gold

Nature Reviews Drug Discovery volume 10, page 397 (2011)Cite this article

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Abstract

A comprehensive and collaborative strategy to enable the investigation of new uses of approved and abandoned drug compounds could advance translational research.

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References

  1. Paul, S. M. et al. How to improve R&D productivity: the pharmaceutical industry's grand challenge. Nature Rev. Drug Discov. 9, 203–214 (2010).

    CAS  Google Scholar 

  2. US FDA. http://www.fda.gov/ForIndustry/DevelopingProductsforRareDiseasesConditions /HowtoapplyforOrphanProductDesignation/ucm216147.htm (2010).

  3. Huang, R. et al. The NCGC Pharmaceutical Collection: A Comprehensive Resource of Clinically Approved Drugs Enabling Repurposing and Chemical Genomics Sci. Transl. Med. 3, 80ps16 (2011).

    Article  Google Scholar 

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  1. Francis S. Collins, M.D., Ph.D., is Director of the National Institutes of Health, Bethesda, Maryland 20892, USA.,

    Francis S. Collins

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  1. Francis S. Collins
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Correspondence to Francis S. Collins.

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The author declares no competing financial interests.

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Collins, F. Mining for therapeutic gold. Nat Rev Drug Discov 10, 397 (2011). https://doi.org/10.1038/nrd3461

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