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Antiviral drugs

Protection against influenza B infection

Nature Reviews Drug Discovery volume 11, page 750 (2012)Cite this article

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This study reported the identification of three human monoclonal antibodies that protected mice against lethal challenge from two antigenically distinct lineages of influenza B viruses that are responsible for a large part of the annual flu burden. The authors showed that two antibodies (CR8033 and CR8071) recognized distinct conserved epitopes in the head region of influenza B haemagglutinin, whereas CR9114 bound to a conserved epitope in the haemagglutinin stem and protected mice against both influenza A and B viruses.

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ORIGINAL RESEARCH PAPER

  1. Dreyfus, C. et al. Highly conserved protective epitopes on influenza B viruses. Science 9 Aug 2012 (doi:10.1126/science.1222908)

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Authors
  1. Charlotte Harrison
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Harrison, C. Protection against influenza B infection. Nat Rev Drug Discov 11, 750 (2012). https://doi.org/10.1038/nrd3863

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