Abstract
Randomized, placebo-controlled, clinical trials tell us whether a drug works, but they normally fail to reveal whether a drug works better than existing therapies. The increasing consideration now being given to the cost-effectiveness of available treatment options should spur a move towards more comparative trials.
Enjoying our latest content?
Log in or create an account to continue
- Access the most recent journalism from Nature's award-winning team
- Explore the latest features & opinion covering groundbreaking research
or
References
Khan, A., Khan, S. R., Leventhal, R. M. & Brown, W. A. Symptom reduction and suicide risk among patients treated with placebo in antipsychotic clinical trials: an analysis of the Food and Drug Administration Database. Am. J. Psychiatry 158, 1449–1454 (2001).
Rights and permissions
About this article
Cite this article
New money for old rope?. Nat Rev Drug Discov 1, 93 (2002). https://doi.org/10.1038/nrd731
Issue date:
DOI: https://doi.org/10.1038/nrd731
